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Millipore and Barnstead Laboratory Water Filtration

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Water Treatment

Water Use In Blood Fractionation

An interesting fact is that of the millions of pints of blood donated per year approximately 10 percent of the blood is lost due to the fact that it becomes outdated before it can be used. This loss is not negligence or inefficiency. This loss is a result form the fact that human blood by present day methods of storage of 4^oC will only keep for 21 days before becoming unusable.

At about -80^oC red blood cells can be stored for almost indefinitely. While maintaining a temperature such as this is not problematic with today's cooling equipment keeping blood cells at this temperature without damaging them is a challenge. This is because as the temperature drops ice crystals form in the cells. This causes the cells to rupture and/or can change the salt concentration inside. Either way the results are often detrimental to the red blood cells being stored.

One surefire way to avoid this is to exchange the cells water content temporarily using a substance that does not freeze nor leave the cells unfit for use later. For this to occur a purified glycerol is used. Blood that has been treated this way can be stored for four years or more and has been used in transfusions with excellent results.

This technique uses centrifugation of blood in special fractionation equipment. What occurs is that whole blood cells and plasma enter an expendable plastic liner in the fractional chamber. The blood separate into tow fractions while spinning. Red cells will clump along the outer perimeter of the spinning liner. Plasma will drain out from the liner near the center of the rotation. Once all the plasma is drained off the red cell mass is infused with biopure water solutions of glycerol all while slowly increasing the concentrations.

This infusion will continue until the glycerol concentration is 35% in the red blood cells. This is when the plastic liner is removed from the fractionator and refrigerated at -80^oC. Plasma collected this way is saved and refrigerated seperatley. When the cells are needed they are thawed out at room temperature placed in the liner again and into the fractionator. Then the infusion process is reversed. The glycerols is removed during a series of rinses with each one containing less glycerol at its completion.The solvent used can be any one of several parenteral fluids made with biopure water or it can be a plasma fraction.

One interesting fact about this technique is that no cases of serum hepatitis have resulted from transfusions made with glycerolized blood. It seems that the glycerolization and deglycerolizatoin process eliminates the hepatitis virus.

Primer: Water Use In Research And Medicine

Water The Cleansing Agent

Water Use In Tissue Cell Culture

Water Usage In Pharmaceuticals

Pyrogens In Research And Medicine

Water Use In Blood Fractionation

Water Use In Cryobiology

General Use of Water in Research and Medicine

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Short Lead times.
Lab Water Deionizer

P12XL4
APS Polaris XL 4 Lab Water System

Retail Price : ~~US$6,499.00~~
Todays Price : US$4,650.00

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APS Polaris D2 Water System with Quality Meter

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Todays Price : US$2,570.25

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APS Polaris D3 Water System with Quality Meter

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Todays Price : US$2,830.20

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APS Polaris D1 Water System with Quality Meter

Retail Price : ~~US$2,118.94~~
Todays Price : US$1,761.72

TAKING PRE-ORDERS

Short lead Time.

This high capacity four housing lab water system is designed to provide up to 3 l.p.m. of ultrapure water exceeding ASTM and CAP Type I, II or III specifications.

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PROUDLY MADE IN THE USA

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APS Polaris D2 Water System with Quality Meter

This dual housing is designed to provide 1 g.p.m. of ultrapure water exceeding ASTM and CAP Type II specifications.

Comparable to Barnstead D4521

Operating Manual

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PROUDLY MADE IN THE USA

Dimensions : 18" W X 28" H X 6" D

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APS Polaris D3 Water System with Quality Meter

This high capacity triple housing is designed to provide 1 g.p.m. of ultrapure water exceeding ASTM and CAP Type II specifications.

Operating Manual

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PROUDLY MADE IN THE USA

Dimensions : 23" W X 28" H X 6" D

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APS Polaris D1 Water System with Quality Meter

This compact single housing is designed to provide 1 g.p.m. of ultrapure water exceeding ASTM and CAP Type II specifications.

Comparable to Barnstead D4511

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PROUDLY MADE IN THE USA

Dimensions : 12" W X 28" H X 6" D

Operating Manual

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Best
Lab Water System

50132372
Barnstead MicroPure UV/UF-ST

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Todays Price : US$6,959.80

50132373
Barnstead MicroPure UV

Retail Price : ~~US$6,750.00~~
Todays Price : US$5,737.50

Barnstead MicroPure Laboratory Water Purification System - Provides Type I Ultrapure Water.

Systems come with the filters. Does not require a permanent feed source. Portable. Just pour tap or treated water into the internal reservoir to produce ultrapure water.

Replacement filters

This is the replacement for the popular EasyPure UV/UF RF systems.

Operating Manual

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